AVAPRO helps most people with high blood pressure, but it may have unwanted side effects in a few people. All medicines can have side effects. Sometimes they are serious, most of the time they are not. Some common side effects of AVAPRO are: headache, dizziness or light-headedness, unusual tiredness or weakness, fatigue, nausea/vomiting feeling like you might pass out, urinating less than usual or not at all, drowsiness/confusion, mood changes, increased thirst or loss of appetite, nausea and vomiting, swelling, weight gain, shortness of breath