Never exceed the dosage regulations for Angeliq menopause relief tablets, meaning you should never take more than one tablet a day. That includes if you have forgotten to take a dose. If you miss a dose, take your next tabletat the regular time the next day. Women who are experiencing any of the following should not take Angeliq; Undiagnosed abnormal genital bleeding, known or suspected history of breast cancer, known or suspected estrogen-dependent neoplasia, active DVT,PE or history of these conditions, Active arterial thromboembolic disease (for example, stroke and MI) or history of these conditions, renal impairment, known liver impairment or disease, adrenal insufficiency, known protein C, protein S, or antithrombin deficiency, or other knownthrombophilic disorders.