Anaprox has the following boxed Warnings and Precautions: NSAIDs can increase the risk of cardiovascular adverse events, especially in patients who have cardiovascular disease or risk factors for cardiovascular disease. The risk may increase the longer the patient takes the medication. Exercise caution. Caution should be used in patients with ischemic heart disease, cerebrovascular disease, and/or congestive heart failure. NSAIDs such as Anaprox can cause sodium retention, which can result in increased blood pressure and/or worsening heart failure. NSAIDs like Anaprox can increase the incidence of gastrointestinal adverse events such as ulcers, bleeding, perforations, and obstructions of the upper and lower gastrointestinal tract. Before you start taking Anaprox, tell your doctor about:, All the prescription and over-the-counter medications you take, Your allergies, Your health conditions and past medical history, Your pregnancy and breastfeeding status, Some NSAIDs may cause persistent urinary symptoms such as bladder pain, painful urination, increased frequency of urination, blood in the urine, or urinary tract infections. Seek medical care if you experience any of these., Taking Anaprox with other blood thinners can increase the risk of bleeding., NSAIDs can cause blood-related disorders., Anaprox can mask the signs and symptoms of an infection., Anaprox can cause drowsiness, dizziness, blurry vision, ringing of the ears, hearing loss, sleep problems, and depression., Although rare, NSAIDs can cause serious skin reactions. Seek medical care right away if you develop a rash. All the prescription and over-the-counter medications you take, Your allergies, Your health conditions and past medical history, Your pregnancy and breastfeeding status