If you are in a state of diabetic ketoacidosis, you should not take Amaryl. Additionally, do not take Amaryl if you are allergic to sulfa drugs, are under-nourished or have any of the following issues:• Heart disease• Liver disease• Kidney disease• Enzyme deficiency• Adrenal or pituitary gland problemsWhile taking Amaryl you will need to continuously check your blood sugar. Low blood sugar, or hypoglycemia, can affect anyone who has diabetes. Ensure you have a source of sugar with you if you have low blood sugar.If you are taking Amaryl, you should limit your exposure to sunlight and tanning, as this medication can increase your chances to sunburn.Amaryl should be taken more than 4 hours after taking colesevelam.You may need emergency medical attention if you are experiencing any of the following side effects:• Difficulty breathing• Hives• Swelling of the face, lips, tongue, or throat