Alecensa (Alectinib)

What is the active ingredient in Alecensa? The active ingredient is alectinib hydrochloride. What are the inactive ingredients? See the package insert for a full list of inactive ingredients.

Who should avoid taking Alecensa? Do not use Alecensa if you have a known allergy to any of the ingredients., Alecensa should not be used in pregnancy. Female patients should avoid pregnancy during treatment and for one week after discontinuation. Visit our birth control page for more information. Male patients should use contraception during therapy and for three months after discontinuation., Female patients should avoid pregnancy during treatment and for one week after discontinuation. Visit our birth control page for more information., Male patients should use contraception during therapy and for three months after discontinuation. Female patients should avoid pregnancy during treatment and for one week after discontinuation. Visit our birth control page for more information., Male patients should use contraception during therapy and for three months after discontinuation. What are the risks? Tell your doctor if you experience any of the following adverse effects. They could reduce your dose, interrupt your therapy, or discontinue your treatment. Symptomatic bradycardia Slowed heart rate (less than 60 beats per minute) Low blood pressure Chest discomfort Lightheadedness Shortness of breath Muscle pains Difficulty breathing Cough Fever, Symptomatic bradycardia Slowed heart rate (less than 60 beats per minute) Low blood pressure Chest discomfort Lightheadedness Shortness of breath, Slowed heart rate (less than 60 beats per minute), Low blood pressure, Chest discomfort, Lightheadedness, Shortness of breath, Muscle pains, Difficulty breathing, Cough, Fever, Alecensa treatment can cause an increase in liver enzymes. Your doctor should periodically monitor your liver., Alecensa treatment can cause your kidney function to decrease. Your doctor should monitor your kidney function. Symptomatic bradycardia Slowed heart rate (less than 60 beats per minute) Low blood pressure Chest discomfort Lightheadedness Shortness of breath, Slowed heart rate (less than 60 beats per minute), Low blood pressure, Chest discomfort, Lightheadedness, Shortness of breath, Muscle pains, Difficulty breathing, Cough, Fever Slowed heart rate (less than 60 beats per minute), Low blood pressure, Chest discomfort, Lightheadedness, Shortness of breath

What are the common Alecensa side effects? Edema, Constipation, Low-grade anemia, Low-grade lymphocytopenia, Liver enzyme elevation, Hyperbilirubinemia, Muscle pain, Difficulty breathing, Fatigue What are the serious Alecensa side effects? Bradyarrhythmia (see irregular heartbeat page), Endocarditis, Intestinal perforation, High-grade anemia, Bleeding, High-grade lymphocytopenia, Increased creatinine kinase, Kidney impairment, Interstitial lung disease, Pneumonia, Pneumonitis, Pulmonary embolism References: Alex Covey studies chemistry and microbiology as an undergraduate before moving on to pharmacy school and completing his Pharm D.  His professional focus is on early phase clinical research but also has background experience in inpatient hospital, community pharmacy, and specialty compounding.Read More....