Side effects of Afinitor can range from mild to severe. You may require emergency attention if you have trouble breathing, chest pains, swelling of your face, lips, tongue or throat. Taking medications to manage heart or blood pressure (ACE inhibitors) could result in more severe side effects.Common side effects include:• nausea, vomiting• diarrhea or constipation• breathing problems including coughing• nosebleeds• infections• pain or swelling• hair loss• skin problems, including acne, rash dry skin• weight loss, loss of appetite• insomnia• mood swings• dizziness or headaches• high blood sugarShould you experience any of the above side effects, contact your doctor.Find out more about Afinitor side effectsTaking Afinitor can have serious side effects, including:• lung problems, including chest pains, shortness of breath• kidney problems• low blood cell count• sign of infection• liver problems• ulcers or blisters in your mouth• Swelling of the hands, ankles and feet• Slow healing wounds• Easy brusing and bleeding• Extreme tiredness• Missed or heavy periodsNotify your doctor right away if you experience any kidney problems including change in color (bloody) or amount of urine. Kidney problems caused by afinitor can be potentially fatal.Afinitor can also cause fatal liver disease in people who have hepatitis B. It can also cause fatal lung problems.Despite it’s severe side effects, Afinitor is prescribed when your doctor has determined that the benefits outweigh the risks.