Adcirca is a prescription medication used to treat pulmonary arterial hypertension (PAH). Adcirca belongs to the class of medications called phosphodiesterase 5 inhibitors (PDE5). Adcirca has been shown to increase the ability to exercise in patients with PAH. PDE5 is an enzyme responsible for the breakdown of the chemical messenger cGMP. cGMP works by increasing the levels of nitric oxide, which relaxes the blood vessels of the lungs. Increasing blood flow to the lungs helps improve PAH symptoms and increase the ability to exercise. Fact Table Formula C22H19N3O4 License US FDA,
EU EMA Bioavailability Varies Legal status Rx-Only Chemical Name Tadalafil Elimination half-life 17.5 hours Dosage (Strength) 20mg Pregnancy - Brands Cialis, Cidala, Adcirca Protein binding 94% PubChem CID 110635 MedlinePlus a604008 ChEBI 71940 ATC code G04BE08 DrugBank DB00820 KEGG D02008 Routes of administration by mouth